Cushing’s disease is a disorder in which there is an increased secretion of adrenocorticotropic hormone, which leads to immunosuppression. An immunosuppressed client should be placed in a private room if possible. Pityriasis rosea is a bothersome, but usually harmless, skin rash. It is not contagious. Patients with diabetes mellitus normally need not be isolated. Heterochromia iridium, or multicolored irises, is almost always harmless and requires no treatment.