The nurse is caring for a client with myasthenia gravis (MG) who is 14 weeks pregnant. Which of the following does the nurse understand about MG in the pregnant client?

  1. Most women with MG tolerate labor poorly unless they are in excellent physical health.
  2. Approximately 25% to 30% of neonates born to women with MG develop neonatal myasthenia.
  3. MG usually goes into remission with younger clients and causes exacerbation in older clients.
  4. Narcotics must be used with caution due to the risk of respiratory depression in clients who are already at risk for respiratory muscle weakness.
Number 4 is correct.
Rationale: Most women with MG tolerate labor well as it does not affect smooth muscle. Approximately 10 percent to 15 percent of neonates born to women with MG develop neonatal myasthenia. The response of women with MG is unpredictable and can range from remission to exacerbation to continued stability throughout pregnancy. Clients with MG are already at risk for respiratory muscle weakness; regional anesthesia is preferred.