The nurse is caring for a client who is HIV positive and gave birth to a full-term infant. The nurse is teaching the client about infections in HIV-positive infants. Which infection does the nurse understand is the most common opportunistic infection in children and infants with HIV?

Number 4 is correct.

Rationale: Pneumocystis jiroveci pneumonia is the most common opportunistic infection in children with HIV. Hepatitis C and strep throat are not commonly opportunistic infections limited to children with HIV. Although cytomegalovirus may be present in HIV, it is not the most common opportunistic infection.