The nurse is caring for a client with AIDS who is diagnosed with thrush. Which instruction should the nurse give to the client’s caretaker, who will be administering nystatin (Mycostatin) oral solution?

  1. take the medication before meals
  2. take the medication after meals
  3. mix the medication with orange juice
  4. take the medication at bedtime
Number 2 is correct.
Rationale: Oral thrush (candidiasis) occurs when the fungus Candida albicans accumulates on the lining of the mouth. While more likely to occur in babies, this condition also appears in persons with a suppressed immune system. The medication should be swished in the mouth, then either spit out or swallowed. To make the best contact with the oral mucosa, the medication should be taken after meals. The solution should not be diluted with other liquids. The standard frequency of nystatin is four times a day.