A client with hypertension asks the nurse to explain how amlodipine besylate (Norvasc) lowers her blood pressure. The nurse gives which explanation to the client?

  • “It prevents calcium from entering the smooth muscle, which relaxes the blood vessels to lower heart rate and blood pressure.”
  • “It is a diuretic that works by removing extra sodium and water from the body through the kidneys, which helps lower blood pressure.”
  • “It causes the body to produce less angiotensin, which allows blood vessels to relax and open up, therefore reducing blood pressure.”
  • “It lowers blood pressure by lowering the heart rate and the workload of the heart, and decreases the amount of blood pumped out of the heart.”
Norvasc is a calcium channel blocker. Calcium causes the heart to beat stronger and harder, so by blocking it, the blood pressure is lowered. Option 2 describes the action of diuretics, such as furosemide. Option 3 describes ACE (angiotensin-converting enzyme) inhibitors, such as lisinopril. Option 4 describes the action of beta-blockers, such as metoprolol tartrate.